Researchers discover brain tumor’s ‘grow-or-go’ switch
March 10, 2010 by admin · Leave a Comment
Contact: Darrell E. Ward
Darrell.Ward@osumc.edu
614-293-3737
Ohio State University Medical Center
COLUMBUS, Ohio Cancer cells in rapidly growing brain tumors must adjust to periods of low energy or die. When energy levels are high, tumor cells grow and proliferate. When levels are low, the cells grow less and migrate more.
Spotlight on rare tumors in hunt for new cancer treatments
March 7, 2010 by admin · Leave a Comment
Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology Read more
The soluble factor IFN-beta represses tumor growth
March 7, 2010 by admin · Leave a Comment
Contact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
Tumors that grow to a certain size need to form new blood vessels if they are to acquire the oxygen and nutrients that are essential for their continued growth and spread to other sites. Although the molecules and signaling pathways that control this new blood vessel growth are potential targets for the treatment of cancer, they have not been completely defined. Using mouse models of cancer, Jadwiga Jablonska and colleagues, at the Helmholtz Centre for Infection Research, Germany, have now identified the soluble factor IFN-beta as a natural inhibitor of tumor blood vessel growth that limits tumor growth and works by repressing in tumor-infiltrating immune cells known as neutrophils the expression of genes responsible for promoting new blood vessel growth. These results provide a potential explanation as to why IFN therapy is beneficial during the early stages of cancer development. Read more
New treatment to prevent cancer recurrence shows promise in Stanford study
February 21, 2010 by admin · Leave a Comment
Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center
STANFORD, Calif. Glioblastoma is one of the most deadly human brain cancers. Radiation can temporarily shrink a tumor, but they nearly always recur within weeks or months and few patients survive longer than two years after diagnosis.
Tumor mechanism identified
February 21, 2010 by admin · Leave a Comment
Contact: Andrew Gould
andrew.gould@pms.ac.uk
44-139-268-6107
The Peninsula College of Medicine and Dentistry Read more
Personalizing cancer: Creating biomarkers from tumor DNA
February 17, 2010 by admin · Leave a Comment
Contact: Natasha Pinol
npinol@aaas.org
202-326-7088
American Association for the Advancement of Science
Researchers have developed a new technique for tracking cancer by identifying personalized biomarkers from tumor DNA, reports a new study in the 24 February 2010 issue of the journal Science Translational Medicine, published by AAAS, the nonprofit science society. The findings show that next-generation sequencing technology is poised become an important tool in the new era of personalized management of cancer patients.
Drug for advanced kidney cancer shrinks tumors prior to surgery
February 16, 2010 by admin · Leave a Comment
Contact: Ellen de Graffenreid
edegraff@med.unc.edu
919-962-3405
University of North Carolina School of Medicine
Chapel Hill, N.C. - More than 57,000 Americans face a diagnosis of kidney cancer each year. Now patients with advanced disease may soon have another treatment option. Physicians who conducted a pilot study at UNC Lineberger Comprehensive Cancer Center found that therapy before surgery with the drug sorafenib can reduce the size of large tumors and could be safely undertaken administered without adding significantly to the risks of surgery.
Researchers discover second protective role for tumor-suppressor
February 16, 2010 by admin · Leave a Comment
Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center Read more
Researchers create drug to keep tumor growth switched off
February 10, 2010 by admin · Leave a Comment
Contact: Steve Benowitz
sbenowitz@ucsd.edu
619-543-6163
University of California - San Diego
A novel and rapid anti-cancer drug development strategy has resulted in a new drug that stops kidney and pancreatic tumors from growing in mice. Researchers at the Moores Cancer Center at the University of California, San Diego, have found a drug that binds to a molecular “switch” found in cancer cells and cancer-associated blood vessels to keep it in the “off” position.
Researchers discover new way to kill pediatric brain tumors
February 8, 2010 by admin · Leave a Comment
Contact: Michael C. Purdy
purdym@wustl.edu
314-286-0122
Washington University School of Medicine
Researchers at Washington University School of Medicine in St. Louis have shown once again that “ready, fire, aim,” nonsensical though it may sound, can be an essential approach to research.
