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New hope for better treatment for a rising cancer

May 12, 2010 by admin · Leave a Comment 

Contact: Dr Srinivasan Madhusudan
srinivasan.madhusudan@nottingham.ac.uk
44-011-582-31850
University of Nottingham
Poor diet, too much alcohol, smoking and increasing obesity could be leading to an epidemic of oesophageal and upper stomach cancer, according to a leading UK team of specialists at The University of Nottingham and Nottingham University Hospitals.

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Nuclear matrix proteins contribute to differentiation of gastric cancer cells

May 6, 2010 by admin · Leave a Comment 

Contact: Ye-Ru Wang
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Gastric cancer is the most common malignant gastrointestinal cancer and accounts for 25% of cancer deaths. Nuclear matrix, a filamentous protein framework for eukaryotic cellular chromatin, closely relates to DNA duplication and transcription. Research on nuclear matrix proteins will provide insight into how tumors developed.

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Study examines incidence of gastric cancer

May 3, 2010 by admin · Leave a Comment 

Contact: NCI Office of Media Relations
ncipressofficers@mail.nih.gov
301-496-6641
JAMA and Archives Journals

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Promising hormone may help reduce malnutrition in gastric cancer patients

March 30, 2010 by admin · Leave a Comment 

Contact: Alissa J. Cruz
media@gastro.org
301-272-1603
American Gastroenterological Association
In gastric cancer patients who have had part or all of their stomach removed, the hormone ghrelin may lessen post-operative weight loss and improve appetite, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

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Herceptin and Tykerb effective against a subset of gastric cancers

March 1, 2010 by admin · Leave a Comment 

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
A combination of two targeted therapies already shown to be effective in breast cancer packs an effective one-two punch against a subset of gastric cancers that have a specific genetic mutation, a study at UCLA’s Jonsson Comprehensive Cancer Center has found.

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Team finds link between stomach-cancer bug and cancer-promoting factor

January 5, 2010 by admin · Leave a Comment 

Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign
CHAMPAIGN, lll. — Researchers report that Helicobacter pylori, the only bacterium known to survive in the harsh environment of the human stomach, directly activates an enzyme in host cells that has been associated with several types of cancer, including gastric cancer.

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Does Helicobacter pylori eradication therapy prevent gastric cancer?

September 25, 2009 by admin · Leave a Comment 

Although it has been demonstrated that Helicobacter pylori causes gastric cancer, it is still controversial that whether H. pylori eradication therapy is effective in primary prevention of gastric cancer. This is especially important for Yamagata Prefecture, a region of Japan with the second highest incidence of gastric cancer in the world.

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A breakthrough in gastric carcinogenesis

June 11, 2009 by admin · Leave a Comment 

Checkpoint with forkhead and ring finger (CHFR) is a mitotic stress checkpoint gene whose promoter is frequently methylated in various kinds of cancer. In gastric cancer, CHFR promoter hypermethylation has been reported to lead to chromosome instability (CIN) and genetic instability is one of the hallmarks of human cancer.

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New minimally invasive surgery option for patients with stomach cancer

April 16, 2009 by admin · Leave a Comment 

A novel, minimally invasive surgical approach to treat stomach cancer has been shown to have advantages that may make it a preferable treatment for some patients.

A new study led by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) compares traditional “open” surgery to remove the stomach with laparoscopic gastrectomy – a minimally invasive procedure in which the surgeon removes the stomach while guided by a magnified image projected by a thin, lighted tube with a video camera at its tip, called a laparoscope. The findings demonstrate that while laparoscopic surgeries generally took longer to perform than open procedures, the minimally invasive approach yielded shorter hospital stays, decreased need for postoperative pain relief, fewer complications after surgery, and similar rates of recurrence-free survival after 36 months of follow-up.

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Broccoli sprouts may protect against stomach cancer and ulcers

April 6, 2009 by admin · Leave a Comment 

A small, pilot study in 50 people in Japan suggests that eating two and a half ounces of broccoli sprouts daily for two months may confer some protection against a rampant stomach bug that causes gastritis, ulcers and even stomach cancer.Citing their new “demonstration of principle” study, a Johns Hopkins researcher and an international team of scientists caution that eating sprouts containing sulforaphane did not cure infection by the bacterium Helicobacter pylori (H. pylori). They do not suggest that eating this or any amount of broccoli sprouts will protect anyone from stomach cancer or cure GI diseases.

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