Rectal cancer rates are rising in young individuals
August 22, 2010 by admin · Leave a Comment
A new analysis has found that while colon cancer rates have remained steady over the past several decades among people under the age of 40, rectal cancer rates are increasing in this population across races and in both sexes. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study indicates that greater efforts are needed to diagnose rectal cancer in young individuals who show potential signs of the disease.
A new drug treatment to close the window on colon cancer
July 20, 2010 by admin · Leave a Comment
Tel Aviv University researchers block stress responses in cancer surgery patients to save lives
Cancer surgery wreaks havoc on a body’s immune system and stress hormones exacerbate the problem. As a result, about half of those who undergo surgery for tumor removal experience a recurrence of cancer in the same region or other parts of the body.
New recommendations issued for use of cetuximab in colon cancer therapy
July 16, 2010 by admin · Leave a Comment
UNC’s Goldberg a key contributor
Chapel Hill, NC In a report published in the July 2010 issue of the American Society for Clinical Oncology Post, new recommendations on the use of the drug cetuximab have been issued after officials halted enrollment in a phase III clinical trial in patients with spread of colon cancer into regional lymph nodes whose tumors had been surgically removed.
Hydrophobic proteins: Potential biomarkers for colorectal cancer
June 23, 2010 by admin · Leave a Comment
Colorectal cancer, cancer of the colon and rectum, is a common cause of mortality worldwide. Statistical data showed that the number of deaths caused by colorectal cancer is increasing in both men and women. Proteins are functional components of the cell that regulate the cell’s activity. Understanding the differential expression of proteins in colorectal cancer and normal tissues will lead to a better understanding of the development of the disease, furthermore, these proteins may serve as biomarkers for treatment or detection of the disease. Hydrophobic proteins play a vital role in various cellular processes, by virtue of their cellular location, and may serve as a target for drug-targeted therapy.
Gut bacteria could be key indicator of colon cancer risk
June 21, 2010 by admin · Leave a Comment
CHAPEL HILL The human body contains more bacteria than it does cells. These bacterial communities can have a positive effect on our health, by training our immune systems and helping to metabolize the foods we eat. But they can also set us up to develop digestive disorders, skin diseases, and obesity.
Scientists move closer to pinpointing gene involved in bowel cancer spread
Contact: Emma Dickinson
edickinson@bmjgroup.com
44-020-738-36529
BMJ-British Medical Journal Read more
Bacteria as a predicter of colorectal cancer
May 24, 2010 by admin · Leave a Comment
Contact: Garth Hogan
ghogan@asmusa.org
American Society for Microbiology
Recent findings suggest that bacteria residing in the the human intestinal tract may be associated with an individual’s risk of developing colon cancer. Scientists from the University of Florida present their research today at the 110th General Meeting of the American Society for Microbiology in San Diego, CA.
Suppressing activity of common intestinal bacteria reduces tumor growth
May 8, 2010 by admin · Leave a Comment
Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego Read more
A potential therapeutic target for colon cancer
May 6, 2010 by admin · Leave a Comment
Contact: Ye-Ru Wang
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Colorectal cancer (CRC) is one of the major causes of cancer death in the developed countries. Accumulated evidences indicate that lipid metabolism, especially the one in the arachidonic acid (AA)-pathway, appears to play a critical role in the development of CRC. The peroxisome proliferator-activated receptor-γ(PPAR-γ) gene, one of the most important components of the AA-pathway, has been verified to express in a variety of tumor cells. Many studies have been performed about the association between the polymorphism 34 C>G of PPAR-γgene and CRC, but got conflicting results.
Stool DNA testing could play expanded role in colon cancer prevention
May 3, 2010 by admin · Leave a Comment
Contact: Amy Tieder
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
NEW ORLEANS — Research teams led by Mayo Clinic have demonstrated for the first time that two types of colorectal pre-cancers can be detected through noninvasive stool DNA testing. The two studies being presented demonstrate that stool DNA testing may be useful for detection of premalignant dysplasia in patients with inflammatory bowel disease (IBD) and of an important type of colorectal pre-cancer called serrated polyps. The findings were presented at Digestive Disease Week 2010 (http://www.ddw.org/wmspage.cfm?parm1=679), the annual meeting of the American Gastroenterological Association.
