Researchers find that one type of stem cell creates a niche for another type in bone marrow

Understanding how blood stem cells are maintained within the niche offers new opportunities to exploit them therapeutically

Cold Spring Harbor, N.Y. – Hematopoietic stem cells (HSCs) have two unique abilities that are prized by medical researchers: to self-renew and to develop into any kind of blood cell, which enables them to replenish the entire blood and immune system. Scientists have traced these qualities to a distinct locale or niche within the bone marrow that HSCs home in on, but the identity and function of the niche-forming constituents have not been clearly defined.

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Behavior therapy effective in reducing tics in children with Tourette syndrome, study finds

Contact: Mark Wheeler
mwheeler@mednet.ucla.edu
310-794-2265
University of California - Los Angeles Read more

Discovery of rare genetic mutation could help battle Tourette syndrome

Contact: Karen N.Peart
karen.peart@yale.edu
203-432-1326
Yale University
A single, very unusual family with Tourette syndrome (TS) has led Yale School of Medicine researchers to identify a rare mutation in a gene that is required to produce histamine. The finding provides a new framework to understand many years of data on the role of histamine function in the brain and points to a potentially novel approach to treatment of tics and Tourette.

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Deep brain stimulation may be effective treatment for Tourette’s syndrome

Deep brain stimulation may be a safe and effective treatment for Tourette syndrome, according to research published in the October 27, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.

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