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Nano-sized advance toward next big treatment era in dentistry

June 29, 2010 by admin · Leave a Comment 

Scientists are reporting an advance toward the next big treatment revolution in dentistry — the era in which root canal therapy brings diseased teeth back to life, rather than leaving a “non-vital” or dead tooth in the mouth. In a report in the monthly journal ACS Nano, they describe a first-of-its-kind, nano-sized dental film that shows early promise for achieving this long-sought goal.

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Technique yields potential biological substitute for dental implants

May 23, 2010 by admin · Leave a Comment 

Contact: Alex Lyda
alyda@columbia.edu
212-305-0820
Columbia University Medical Center Read more

Formula for making teeth coming soon?

March 14, 2010 by admin · Leave a Comment 

Contact: Jukka Jernvall
jukka.jernvall@helsinki.fi
358-407-403-478
University of Helsinki
Each cusp of our teeth is regulated by genes which carefully control the development. A similar genetic puzzle also regulates the differentiation of our other organs and of all living organisms. A team of researchers at the Institute of Biotechnology of the University of Helsinki has developed a computer model reproducing population-level variation in complex structures like teeth and organs. The research takes a step towards the growing of correctly shaped teeth and other organs. The results were published last week in Nature, the esteemed science journal.

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New study introduces the prospect for concurrent antiangiogenic/antitumorigenic therapy

March 4, 2010 by admin · Leave a Comment 

Contact: Ingrid Thomas
ithomas@aadronline.org
703-299-8084
International & American Association for Dental Research
Washington, DC, USA – Today, during the 39th Annual Meeting of the American Association for Dental Research, convening at the Walter E. Washington Convention Center in Washington, DC, lead researcher M. Tong, The Ohio State University, will present a poster of a study titled “Epithelial-to-Endothelial Transition: An Epithelial Phenotypic Modulation Facilitating Oral-Squamous-Cell Carcinoma Progression.” Tong and a team of researchers have reported that oral squamous cell carcinoma (OSCC) cells endogenously produce exceptionally high levels of vascular endothelial growth factor (VEGF). In addition to its proangiogenic function, they observed that VEGF fulfills an autocrine-paracrine role in OSCC by directly promoting OSCC cell proliferation and invasion.

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Genetic study reveals the origins of cavity-causing bacteria

December 22, 2009 by admin · Leave a Comment 

Contact: Tamsin Milewicz
press@plos.org
44-122-346-3339
Public Library of Science
Researchers have uncovered the complete genetic make-up of the cavity-causing bacterium Bifidobacterium dentium Bd1, revealing the genetic adaptations that allow this microorganism to live and cause decay in the human oral cavity. The study, led by Marco Ventura’s Probiogenomics laboratory at the University of Parma, and Prof. Douwe van Sinderen and Dr Paul O’Toole of the Alimentary Pharmabiotic Centre at University College Cork, is published December 24 in the open-access journal PLoS Genetics.

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