First clinical trial of gene therapy for pain reported by U-M neurologists

New study suggests treatment may provide substantial relief

Ann Arbor, Mich. — In the first clinical trial of gene therapy for treatment of intractable pain, researchers from the University of Michigan Department of Neurology observed that the treatment appears to provide substantial pain relief.

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UC Davis pain research may pave the way to understanding and controlling chronic pain

Researchers at the University of California, Davis have discovered a “cross-talk” between two major biological pathways that involve pain—research that may pave the way to new approaches to understanding and controlling chronic pain.

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Experimental drug more potent, longer lasting than morphine

Less likely to cause constipation

MAYWOOD, Ill. — A little-known morphinelike drug is potentially more potent, longer lasting and less likely to cause constipation than standard morphine, a study led by a Loyola University Health System anesthesiologist has found.

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People with chronic pain face complex dilemmas and life-changing decisions

Coping with chronic pain can affect every aspect of a person’s life and cause conflict between what their mind wants to achieve and what their body allows them to do, according to research in the December issue of the Journal of Nursing and Healthcare of Chronic Illness.

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Acute pain is eased with the touch of a hand

There may be a very good reason that people naturally clutch their hand after receiving an injury. A new report published online on September 23 in Current Biology shows that self-touch offers significant relief for acute pain under experimental conditions. The researchers suggest that the relief comes from a change in the brain’s representation of the rest of the body.

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Compound boosts marijuana-like chemical in the body to relieve pain at injury site

Drug created by UCI, Italian team inhibits enzyme that breaks down anandamide

Irvine, Calif., Sept. 20, 2010 — American and Italian researchers have found that a novel drug allows anandamide – a marijuana-like chemical in the body – to effectively control pain at the site of an injury.

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Music on prescription could help treat emotional and physical pain

New research into how music conveys emotion could benefit the treatment of depression and the management of physical pain.

Using an innovative combination of music psychology and leading-edge audio engineering the project is looking in more detail than ever before at how music conveys emotion.

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Mount Sinai researchers find new target to improve pain management

Mount Sinai researchers identify new therapeutic target to improve pain management after chronic morphine administration

Researchers from Mount Sinai School of Medicine have discovered a major mechanism underlying the development of tolerance to chronic morphine treatment. The discovery may help researchers find new therapies to treat chronic pain, and reduce tolerance and side effects associated with morphine use. The findings are published in the July 20th issue of Science Signaling.

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Smoked cannabis reduces chronic pain

Randomized controlled trial

For people suffering chronic pain, smoked cannabis reduces pain, improves mood and helps sleep, according to new research published in CMAJ (Canadian Medical Association Journal)

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Research demonstrates benefits of medical cannabis as a treatment for chronic pain

The medicinal use of cannabis has been debated by clinicians, researchers, legislators and the public at large for many years as an alternative to standard pharmaceutical treatments for pain, which may not always be effective and may have unwanted side effects. A new study by McGill University Health Centre (MUHC) and McGill University researchers provides evidence that cannabis may offer relief to patients suffering from chronic neuropathic pain. The results of the groundbreaking study are published in the latest issue of the Canadian Medical Association Journal.

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