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Team discovers new type of anti-malarial compound

September 3, 2010 by admin · Leave a Comment 

Clinical trials for promising new drug candidate are planned

LA JOLLA, CA – August 30, 2010 –– An international team led by scientists from The Scripps Research Institute, the Swiss Tropical Institute, the Genomics Institute of the Novartis Research Foundation and the Novartis Institute for Tropical Diseases has discovered a promising new drug candidate that represents a new class of drug to treat malaria. Clinical trials for the compound are planned for later this year.

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Scientists develop new drug treatment for malaria

August 15, 2010 by admin · Leave a Comment 

As part of the £1.5 million project, researchers are now testing the drug to determine how the treatment could progress to clinical trials. The drug is made from simple organic molecules and will be cheaper to mass produce compared to existing therapies.

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‘Needle-free’ intervention as natural vaccine against malaria

August 10, 2010 by admin · Leave a Comment 

Preventative treatment with affordable and safe antibiotics in people living in areas with intense malaria transmission has the potential to act as a ‘needle-free’ natural vaccine against malaria

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New methods, new math speed detection of drug-resistant malaria

August 1, 2010 by admin · Leave a Comment 

Researchers at Case Western Reserve University developed techniques to quickly identify evolution of drug resistance in strains of malaria. Their goal is to enable the medical community to react quickly to inevitable resistance and thereby save lives while increasing the lifespan of drugs used against the disease.

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Antibiotics for the prevention of malaria

July 20, 2010 by admin · Leave a Comment 

If mice are administered an antibiotic for three days and are simultaneously infected with malaria, no parasites appear in the blood and the life-threatening disease is averted. In addition, the animals treated in this manner also develop robust, long-term immunity against subsequent infections. This discovery was made by the team headed by Dr. Steffen Borrmann from the Department of Infectious Diseases at Heidelberg University Hospital in cooperation with Dr. Kai Matuschewski of the Max Planck Institute for Infection Biology in Berlin. The scientists think that safe and affordable prophylaxis with antibiotics in residents of areas with high malaria transmission has the potential to be used as a natural “needle-free” vaccination against malaria (Science Translational Medicine, July 14, 2010).

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Antibiotics for the prevention of malaria

July 19, 2010 by admin · Leave a Comment 

Antibiotic treatment during the liver stage of malaria generates strong protective immunity

If mice are administered an antibiotic for three days and are simultaneously infected with malaria, no parasites appear in the blood and life-threatening disease is averted. In addition, the animals treated in this manner also develop robust, long-term immunity against subsequent infections. This discovery was made by the team headed by Dr. Steffen Borrmann from the Department of Infectious Diseases at Heidelberg University Hospital in cooperation with Dr. Kai Matuschewski of the Max Planck Institute for Infection Biology in Berlin. The scientists think that safe and affordable prophylaxis with antibiotics in residents of areas with high malaria transmission has the potential to be used as a natural “needle-free” vaccination against malaria (Science Translational Medicine, 14 July 2010).

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Alternative pathway to malaria infection identified

June 16, 2010 by admin · Leave a Comment 

Discovery of a key red cell molecule used by the malaria parasite gives renewed hope for an effective vaccine in the future, according to an international team of researchers.

Plasmodium falciparum, a blood parasite that causes malaria by invading and multiplying in the red blood cells, kills 1 to 2 million people annually.

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Novel anti-malarial drug candidate found by UT Southwestern researchers

May 24, 2010 by admin · Leave a Comment 

Contact: Aline McKenzie
aline.mckenzie@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
DALLAS – May 25, 2010 – As part of a multicenter study, UT Southwestern Medical Center researchers have identified a series of chemical compounds that might serve as starting points for the identification of new classes of anti-malarial drugs.

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Scientists release data on potential new treatment targets for malaria

May 18, 2010 by admin · Leave a Comment 

Contact: Summer Freeman
summer.freeman@stjude.org
901-595-3061
St. Jude Children’s Research Hospital Read more

New twist on potential malaria drug target acts by trapping parasites in cells

May 13, 2010 by admin · Leave a Comment 

Contact: Christina Roache
croache@hsph.harvard.edu
617-384-8979
Harvard School of Public Health
Boston, MA — Harvard School of Public Health (HSPH) researchers and colleagues seeking to block invasion of healthy red blood cells by malaria parasites have instead succeeded in locking the parasites within infected blood cells, potentially containing the disease.

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