Unveiling malaria’s ‘cloak of invisibility’
January 17, 2012 by admin · Leave a Comment
The discovery by researchers from the Walter and Eliza Hall Institute of a molecule that is key to malaria’s ‘invisibility cloak’ will help to better understand how the parasite causes disease and escapes from the defenses mounted by the immune system.
First results from Phase 3 trial show malaria vaccine candidate reduces the risk of malaria
October 17, 2011 by admin · Leave a Comment
Seattle, 18 October 2011 First results from a large-scale Phase III trial of RTS,S, published online today in the New England Journal of Medicine (NEJM), show the malaria vaccine candidate to provide young African children with significant protection against clinical and severe malaria with an acceptable safety and tolerability profile. The results were announced today at the Malaria Forum hosted by the Bill & Melinda Gates Foundation in Seattle, Washington.
Modified vaccine shows promise in preventing malaria
September 25, 2011 by admin · Leave a Comment
Continuing a global effort to prevent malaria infections, Michigan State University researchers have created a new malaria vaccine one that combines the use of a disabled cold virus with an immune system-stimulating gene that appears to increase the immune response against the parasite that causes the deadly disease.
Researchers discover biochemical weakness of malaria parasite — vaccine to be developed
June 6, 2011 by admin · Leave a Comment
Every year, 10,000 pregnant women and up to 200,000 newborn babies are killed by the malaria parasite. Doctors all around the globe have for years been looking in vain for a medical protection, and now researchers from the University of Copenhagen have found the biochemically weakness of the lethal malaria parasite, and will now start developing a vaccine to combat pregnancy related malaria.
2020 vision of vaccines for malaria, TB and HIV/AIDS
May 24, 2011 by admin · Leave a Comment
In a Nature Perspective Seattle BioMed’s Aderem shares insight into rational vaccine development using new approaches
SEATTLE, WA, May 25, 2011 Collectively, malaria, TB & HIV/AIDS cause more than five million deaths per year nearly the entire population of the state of Washington and represent one of the world’s major public health challenges as we move into the second decade of the 21st century. In the May 26, 2011, edition of the premier scientific journal Nature, Seattle BioMed Director Alan Aderem, Ph.D., along with Rino Rappuoli, Ph.D., Global Head of Vaccines Research for Novartis Vaccines & Diagnostics, discuss recent advances in vaccine development, along with new tools including systems biology and structure-based antigen design that could lead to a deeper understanding of mechanisms of protection. This, in turn, will illuminate the path to rational vaccine development to lift the burden of the world’s most devastating infectious diseases.
Newer antimalarials more effective than quinine against severe malaria
March 14, 2011 by admin · Leave a Comment
Quinine should no longer be the drug of choice for treating severe malaria, according to an updated systematic review by Cochrane researchers. It is now evident that the antimalarial drug artesunate, which is derived from herbs used in Chinese medicine, is more effective at preventing death in patients with severe malaria.
Natural compounds: the future of anti-malarial treatment
March 13, 2011 by admin · Leave a Comment
In the run up to World Malaria Day on the 25th April 2011, BioMed Central’s open access journal Malaria Journal takes a long hard look at the development of natural compounds for use in the fight against malaria.
UIC researcher unveils new approach to blocking malaria transmission
December 3, 2010 by admin · Leave a Comment
University of Illinois at Chicago researcher Dr. John Quigley will describe a promising new approach to blocking malaria transmission during the American Society of Hematology’s annual meeting in Orlando, Fla.
Global map of the sickle cell gene supports ‘malaria hypothesis’
November 1, 2010 by admin · Leave a Comment
At a global scale, the sickle cell gene is most commonly found in areas with historically high levels of malaria, adding geographical support to the hypothesis that the gene, whilst potentially deadly, avoids disappearing through natural selection by providing protection against malaria.
Malarial mosquitoes are evolving into new species, say researchers
October 20, 2010 by admin · Leave a Comment
Two strains of the type of mosquito responsible for the majority of malaria transmission in Africa have evolved such substantial genetic differences that they are becoming different species, according to researchers behind two new studies published today in the journal Science.
