Top

Malaria drug treatment breakthrough

March 22, 2013 by · Leave a Comment 

An international study, involving researchers from Griffith University’s Eskitis Institute, has discovered a molecule which could form the basis of powerful new anti-malaria drugs.

Professor Vicky Avery from Griffith University’s Eskitis Institute is co-author of the paper “Quinolone-3-Diarylethers: a new class of drugs for a new era of malaria eradication” which has been published in the journal Science Translational Medicine.

Read more

Injection-free vaccination technique could address global vaccine challenge for HIV, malaria

February 4, 2013 by · Leave a Comment 

Scientists at King’s College London have demonstrated the ability to deliver a dried live vaccine to the skin without a traditional needle, and shown for the first time that this technique is powerful enough to enable specialised immune cells in the skin to kick-start the immunising properties of the vaccine.

Read more

Penn team developing new class of malaria drugs using essential calcium enzyme

December 27, 2012 by · Leave a Comment 

Calpain, a calcium-regulated enzyme, is essential to a host of cellular processes, but can cause severe problems in its overactivated state. It has been implicated as a factor in muscular dystrophy, AIDS, Alzheimer’s disease, multiple sclerosis, and cancer. As such, finding and exploiting calpain inhibitors is an important area of research.

Read more

New malaria drug requires just one dose and appears twice as effective as existing regimen

October 17, 2012 by · Leave a Comment 

Scientists are reporting development of a new malaria drug that, in laboratory tests, has been twice as effective as the best current medicine against this global scourge and may fight off the disease with one dose, instead of the multiple doses that people often fail to take. A report on the drug appears in ACS’ Journal of Medicinal Chemistry.

Read more

Biologists produce potential malarial vaccine from algae

May 15, 2012 by · Leave a Comment 

Biologists at the University of California, San Diego have succeeded in engineering algae to produce potential candidates for a vaccine that would prevent transmission of the parasite that causes malaria, an achievement that could pave the way for the development of an inexpensive way to protect billions of people from one of the world’s most prevalent and debilitating diseases. Initial proof-of-principle experiments suggest that such a vaccine could prevent malaria transmission.

Read more

Drug could reverse scourge of cerebral malaria for survivors

April 30, 2012 by · Leave a Comment 

Michigan State University researchers, with the help of a groundbreaking medical device, are starting a clinical trial in Africa they hope will provide relief for the hundreds of thousands of children who survive cerebral malaria but are left stricken with epilepsy or other neurologic disorders.

Read more

Unveiling malaria’s ‘cloak of invisibility’

January 17, 2012 by · Leave a Comment 

The discovery by researchers from the Walter and Eliza Hall Institute of a molecule that is key to malaria’s ‘invisibility cloak’ will help to better understand how the parasite causes disease and escapes from the defenses mounted by the immune system.

Read more

First results from Phase 3 trial show malaria vaccine candidate reduces the risk of malaria

October 17, 2011 by · Leave a Comment 

Seattle, 18 October 2011 — First results from a large-scale Phase III trial of RTS,S, published online today in the New England Journal of Medicine (NEJM), show the malaria vaccine candidate to provide young African children with significant protection against clinical and severe malaria with an acceptable safety and tolerability profile. The results were announced today at the Malaria Forum hosted by the Bill & Melinda Gates Foundation in Seattle, Washington.

Read more

Modified vaccine shows promise in preventing malaria

September 25, 2011 by · Leave a Comment 

Continuing a global effort to prevent malaria infections, Michigan State University researchers have created a new malaria vaccine – one that combines the use of a disabled cold virus with an immune system-stimulating gene – that appears to increase the immune response against the parasite that causes the deadly disease.

Read more

Researchers discover biochemical weakness of malaria parasite — vaccine to be developed

June 6, 2011 by · Leave a Comment 

Every year, 10,000 pregnant women and up to 200,000 newborn babies are killed by the malaria parasite. Doctors all around the globe have for years been looking in vain for a medical protection, and now researchers from the University of Copenhagen have found the biochemically weakness of the lethal malaria parasite, and will now start developing a vaccine to combat pregnancy related malaria.

Read more

Next Page »

Bottom