Umbilical cord blood-derived stem cells studied for lupus therapy
April 10, 2011 by admin · Leave a Comment
Tampa, Fla. (April 11, 2011) Human umbilical cord blood-derived mensenchymal stem cells (uMSCs) have been found to offer benefits for treating lupus nephritis (LN) when transplanted into mouse models of systemic lupus erythematosus (SLE). SLE is an autoimmune disease with “myriad immune system aberrations” characterized by diverse clinical conditions, including LN, a leading cause of morbidity and mortality for patients with SLE.
New lupus drug results from Scripps Research technology
March 8, 2011 by admin · Leave a Comment
The long path to Benlysta emphasizes importance of basic research
LA JOLLA, CA March 9, 2011 For Immediate Release Scientific advances at The Scripps Research Institute were key to laying the foundation for the new drug Benlysta® (belimumab), approved today by the U.S. Food and Drug Administration. Benlysta®, which treats the most common type of lupus, is the first in a new class of pharmaceuticals that prevents the body from attacking its own critical tissues.
Research uncovers key to understanding cause of lupus
January 31, 2011 by admin · Leave a Comment
Potentially impacting future diagnosis and treatment of lupus, an immune illness affecting more than 5 million people worldwide, researchers at the Virginia-Maryland Regional College of Veterinary Medicine at Virginia Tech have likely uncovered where the breakdown in the body’s lymphocyte molecular regulatory machinery is occurring.
Researchers come a long way in a decade of research is helping lupus patients
November 3, 2010 by admin · Leave a Comment
Patients have better treatment options than ever before
Today, individuals with lupus nephritis benefit from better treatments than a decade ago, according to a review appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The article suggests that patients with the disease can now live full lives without suffering from many treatment-related side effects that plagued them in the past. In the future, patients will likely experience additional benefits from treatment strategies currently being explored in clinical trials.
New class of biomolecules triggered in response to respiratory virus infection
October 24, 2010 by admin · Leave a Comment
Long, non-protein-coding RNAs may help regulate innate immunity
For the first time, scientists have discovered that a poorly understood class of RNA produced in a mammal’s cells during a respiratory virus attack may affect the outcome of the infection. Their findings are reported today in mBio, a journal of the American Society for Microbiology.
Discovery highlights promise of new immune system-based therapies
September 14, 2010 by admin · Leave a Comment
BOSTON–A new focus on the immune system’s ability to both unleash and restrain its attack on disease has led Dana-Farber Cancer Institute scientists to identify cells in mice that prevent the immune system from attacking the animals’ own cells, protecting them from autoimmune diseases such as multiple sclerosis, type 1 diabetes, and lupus.
Researchers uncover biological rationale for why intensive lupus treatment works
July 26, 2010 by admin · Leave a Comment
DALLAS July 27, 2010 Researchers at UT Southwestern Medical Center have uncovered the biological rationale for why large doses of corticosteroids given repeatedly over several weeks may help individuals with lupus, a chronic inflammatory disease that affects more than 1 million people in the U.S.
Genealogy may affect clinical differences in systemic lupus erythmatosus patients
Rome, Italy, Friday 18 June 2010: The effects of Systemic Lupus Erythematosus (SLE) may differ based on the individual patient’s genealogical heritage, according to results of a new study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. In particular, the study reinforced differences in SLE phenotype found between Northern and Southern European subpopulations.
Important control mechanism behind autoimmune diseases discovered
May 3, 2010 by admin · Leave a Comment
Contact: Katarina Sternudd
katarina.sternudd@ki.se
46-852-483-895
Karolinska Institutet
Researchers at the Swedish medical university Karolinska Institutet have discovered a new control mechanism in our immune system. The discovery is of potential significance to the treatment of serious diseases such as MS (multiple sclerosis), rheumatoid arthritis, and SLE (Systemic lupus erythematosus).
Rescue NET for lupus patients
May 2, 2010 by admin · Leave a Comment
Contact: Arturo Zychlinsky
zychlinsky@mpiib-berlin.mpg.de
49-302-846-0300
Max-Planck-Gesellschaft
Lupus is a disease where the immune system attacks healthy cells of the body. This leads to progressive damage of different tissues and organs. The classical characteristic of the disease is the so-called butterfly rash in the face. Many Lupus patients eventually die of kidney failure. Scientists at the Max Planck Institute for Infection Biology in Berlin together with medical scientists from the University of Erlangen succeeded in elucidating basic principles of the disease. This opens up new perspectives for methods that might enable early diagnosis and treatment of Lupus patients with a high risk at kidney failure. (PNAS, May 3, 2010)
