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New approach may help dialysis patients fight anemia

November 28, 2010 by admin · Leave a Comment 

A drug called FG-2216 stimulates ‘EPO’ production — even in patients without kidneys

A new drug called FG-2216 can stimulate production of the hormone erythropoietin (EPO) in dialysis patients—possibly offering a new approach to treatment of kidney disease-related anemia, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

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Pomegranate juice: Beyond antioxidants, potential benefits for dialysis patients

November 17, 2010 by admin · Leave a Comment 

Pomegranate juice reduces damage to tissues, inflammation and infections

Studies in recent years have claimed multiple health benefits of pomegranate juice, including that it is a good source of antioxidants and lowers both cholesterol and blood pressure, especially in diabetic and hypertensive patients. A preliminary study now suggests that it can ward off a number of complications in kidney disease patients on dialysis, including the high morbidity rate due to infections and cardiovascular events, according to a paper being presented at the American Society of Nephrology’s 43rd Annual Meeting and Scientific Exposition in Denver, CO.

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Simple blood test helps predict chronic kidney disease

October 20, 2010 by admin · Leave a Comment 

3 biomarkers provide clues about how kidney disease develops

Measuring three biomarkers in a single blood sample may improve physicians’ ability to identify patients at high risk of developing chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

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Researchers develop method for curbing growth of crystals that form kidney stones

October 13, 2010 by admin · Leave a Comment 

Researchers have developed a method for curbing the growth of crystals that form cystine kidney stones. Their findings, which appear in the latest issue of the journal Science, may offer a pathway to a new method for the prevention of kidney stones.

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A new target in polycystic kidney disease

September 12, 2010 by admin · Leave a Comment 

Experimental drug decreases size and number of cysts in animal model

In work suggesting a new approach to treating polycystic kidney disease (PKD), a leading cause of kidney failure, researchers at Children’s Hospital Boston were able to block the formation of fluid-filled cysts, the hallmark of the disease, in a mouse model. Their findings, using a compound that inhibits a receptor known as c-Met, will be published in the September 13th online edition of the Journal of Clinical Investigation.

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UCSF unveils model for implantable artificial kidney to replace dialysis

September 1, 2010 by admin · Leave a Comment 

UCSF researchers today unveiled a prototype model of the first implantable artificial kidney, in a development that one day could eliminate the need for dialysis.

The device, which would include thousands of microscopic filters as well as a bioreactor to mimic the metabolic and water-balancing roles of a real kidney, is being developed in a collaborative effort by engineers, biologists and physicians nationwide, led by Shuvo Roy, PhD, in the UCSF Department of Bioengineering and Therapeutic Sciences.

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Millions of Americans in early stages of kidney disease need stroke monitoring

July 27, 2010 by admin · Leave a Comment 

WINSTON-SALEM, N.C. – Wednesday, July 28, 2010 – Millions of Americans in the early stages of chronic kidney disease (CKD) are at an increased risk of having atrial fibrillation (AF) – a major risk factor for stroke – according to new research by investigators at Wake Forest University Baptist Medical Center.

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Heart beat may provide clues to kidney health

July 9, 2010 by admin · Leave a Comment 

Abnormal rates increase risk of kidney disease

Individuals with a high resting heart rate and a low beat-to-beat heart rate variability have an increased risk of developing kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The findings suggest that the behavior of the autonomic nervous system may be a sentinel marker for late development of certain cases of kidney disease.

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TGen-led studies identify genetic links to kidney disease, kidney failure

June 25, 2010 by admin · Leave a Comment 

Findings released at American Diabetes Association conference in Orlando

PHOENIX, Ariz. — June 26, 2010 — Researchers at the Translational Genomics Research Institute (TGen) will make two presentations at this week’s 70th Scientific Sessions of the American Diabetes Association, June 25-29, in Orlando, Florida.

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Genetically modified cell procedure may prove useful in treating kidney failure

June 21, 2010 by admin · Leave a Comment 

INDIANAPOLIS — A protein whose primary role is in the embryonic development of kidneys may play a future role in treating kidney failure.

Indiana University School of Medicine researchers have successfully treated acute kidney injury in laboratory experiments using cells that were genetically reprogrammed to produce the protein. The research suggests there could be a potential future treatment using such cells delivered intravenously instead of surgically.

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