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Stem cell advance a step forward for treatment of brain diseases

December 6, 2010 by admin · Leave a Comment 

Scientists have created a way to isolate neural stem cells – cells that give rise to all the cell types of the brain – from human brain tissue with unprecedented precision, an important step toward developing new treatments for conditions of the nervous system, like Parkinson’s and Huntington’s diseases and spinal cord injury.

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Natural compound shows promise against Huntington’s disease

November 14, 2010 by admin · Leave a Comment 

LA JOLLA, CA-Fisetin, a naturally occurring compound found in strawberries and other fruits and vegetables, slows the onset of motor problems and delays death in three models of Huntington’s disease, according to researchers at the Salk Institute for Biological Studies. The study, published in the online edition of Human Molecular Genetics, sets the stage for further investigations into fisetin’s neuroprotective properties in Huntington’s and other neurodegenerative conditions.

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Research links huntingtin to neurogenesis

August 11, 2010 by admin · Leave a Comment 

New research finds that a protein that is often mutated in Huntington’s disease (HD) plays an unexpected role in the process of neurogenesis. The research, published by Cell Press in the August 12 issue of the journal Neuron, provides new insight into HD pathology and has even broader implications for human health and disease.

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Huntington’s disease discovery provides new hope for treatment

July 27, 2010 by admin · Leave a Comment 

Australian scientists have identified the behaviour of the mutant protein ‘huntingtin’ which leads to the fatal Huntington’s disease providing potential targets to treat the disease, a University of Melbourne study reveals.

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New approach which can help to predict neurodegenerative diseases

July 25, 2010 by admin · Leave a Comment 

New investigations, initiated by research workers at CIC bioGUNE and led by Dr. Aitor Hierro, have opened possibilities for making progress in the knowledge and prediction of neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS), according to the prestigious journal of The Proceedings of the National Academy of Sciences of the United States of America.

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Scientists make important step toward stopping plaque-like formations in Huntington’s disease

May 20, 2010 by admin · Leave a Comment 

Contact: Tracey DePellegrin Connelly
td2p@andrew.cmu.edu
412-268-1812
Genetics Society of America Read more

Ku70 shown to be critical regulator of DNA damage in Huntington’s disease

May 2, 2010 by admin · Leave a Comment 

Contact: Rita Sullivan
news@rupress.org
212-327-8603
Rockefeller University Press
Ku70, a component of the DNA repair complex, is shown to be a new critical player in the DNA damage-linked pathologies of Huntington’s disease (HD), according to a study in the May 3 issue of the Journal of Cell Biology (www.jcb.org).

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‘Epigenetic’ concepts offer new approach to degenerative disease

April 27, 2010 by admin · Leave a Comment 

Contact: Nicole Kresge
nkresge@asbmb.org
202-316-5447
Federation of American Societies for Experimental Biology
ANAHEIM, CA – In studies on cancer, heart disease, neurological disorders and other degenerative conditions, some scientists are moving away from the “nature versus nurture” debate, and are finding you’re not a creature of either genetics or environment, but both - with enormous implications for a new approach to health.

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Faulty clean-up process may be key event in Huntington’s disease

April 10, 2010 by admin · Leave a Comment 

Contact: Deirdre Branley
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine Read more

Protecting the brain from a deadly genetic disease

February 22, 2010 by admin · Leave a Comment 

Contact: Kathy Wallis
kwallis3@uwo.ca
519-661-2111 x81136
University of Western Ontario
Huntington’s disease (HD) is a cruel, hereditary condition that leads to severe physical and mental deterioration, psychiatric problems and eventually, death. Currently, there are no treatments to slow down or stop it. HD sufferers are born with the disease although they do not show symptoms until late in life. In a new study published in The Journal of Neuroscience, Stephen Ferguson and Fabiola Ribeiro of Robarts Research Institute at The University of Western Ontario identified a protective pathway in the brain that may explain why HD symptoms take so long to appear. The findings could also lead to new treatments for HD.

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