Protein injection shows promise in lowering elevated triglycerides

American Heart Association rapid access journal report

Injecting a protein that helps break down triglycerides may someday help treat an inherited form of high triglycerides, according to a new study in Arteriosclerosis, Thrombosis, and Vascular Biology, an American Heart Association journal.

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Better cholesterol drugs may follow Saint Louis University researcher’s breakthrough

ST. LOUIS – Thanks to a discovery by a Saint Louis University researcher, scientists have identified an important microRNA that may allow us to better control cholesterol levels in blood.

Led by Ángel Baldán, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University and published in a recent issue of Proceedings of the National Academy of Sciences of the United States of America, the study found that the microRNA miR-33, may be key to controlling HDL, or “good” cholesterol levels.

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Scientists find gene for high cholesterol in blood

Contact: Joseph Carey
jcarey@sfbr.org
210-258-9437
Southwest Foundation for Biomedical Research Read more

Compounds in non-stick cookware may be associated with elevated cholesterol in children and teens

Children and teens with higher blood levels of chemicals used in the production of non-stick cookware and waterproof fabrics appear more likely to have elevated total and LDL cholesterol levels, according to a report in the September issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

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Cholesterol Levels Linked to Depression in Elderly

School of Montpellier analysts show us how depression is linked to cholesterol and gender

Did you know the Institute of Health and Medical Research (INSERM) and University of Montpellier financed professionals indicated that regulating ‘good’ and ‘bad’ levels of cholesterol can help stop mental problems among seniors?

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Gene for cholesterol and cardiovascular disease identified through genome scan

Study represents important example of value of genome scanning for identifying potential targets for drug development

PHILADELPHIA – Researchers at the University of Pennsylvania School of Medicine, the Broad Institute, Massachusetts General Hospital, and Alnylam Pharmaceuticals Inc., are some of the first to prove that a gene linked to a disease trait by genome wide association studies (GWAS) can be clinically relevant and an important determinant of disease risk.

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Scientists identify 95 genetic variants associated with cholesterol, triglycerides

ANN ARBOR, Mich.—A global team of researchers co-led by the University of Michigan School of Public Health has discovered or confirmed 95 regions of the human genome where genetic variants are associated with blood cholesterol and triglyceride levels, which are major indicators of heart disease risk.

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Rare and common genetic variations responsible for high triglyceride levels in blood

It can make blood look like cream of tomato soup. Patients with high levels of triglycerides in their blood, a disease called hypertriglyceridemia (HTG) face an increased risk for heart disease and stroke. HTG affects one in 20 people in North America and is also associated with obesity, diabetes and pancreatitis. Most people now understand the importance of LDL, the bad cholesterol and HDL, the good cholesterol, to their overall health. But high triglycerides are like the Rodney Dangerfield of the lipid world: they get less respect and notoriety compared to their cholesterol cousins. Doctors are often uncertain about how best to treat patients with this condition. Understanding the genes that make patients susceptible to HTG could provide clues to newer, better treatments.

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‘Remote control’ for cholesterol regulation discovered in brain

—Circulation of cholesterol is regulated in the brain by the hunger-signaling hormone ghrelin, researchers say. The finding points to a new potential target for the pharmacologic control of cholesterol levels.

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More ‘good’ cholesterol is not always good for your health

Contact: Emily Butler
emily_butler@urmc.rochester.edu
585-273-1757
University of Rochester Medical Center Read more

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