Pinpointing immune system disturbances in celiac disease
February 27, 2010 by admin · Leave a Comment
Contact: Alex Fernandes
a.fernandes@qmul.ac.uk
44-20-788-25378
Queen Mary, University of London
New research has identified four aspects of immune system disturbance which lead to the development of coeliac disease. Nearly 40 different inherited risk factors which predispose to the disease have now been identified. These latest findings could speed the way towards improved diagnostics and treatments for the autoimmune complaint that affects 1 in 100 of the population, and lead to insights into related conditions such as type 1 diabetes.
Scientists pinpoint critical molecule to celiac disease, possibly other autoimmune disorders
September 7, 2009 by admin · Leave a Comment
Findings reveal further detail about protein linked to inflammatory disorders
It was nine years ago that University of Maryland School of Medicine researchers discovered that a mysterious human protein called zonulin played a critical role in celiac disease and other autoimmune disorders, such as multiple sclerosis and diabetes. Now, scientists have solved the mystery of zonulin’s identity, putting a face to the name, in a sense. Scientists led by Alessio Fasano, M.D., have identified zonulin as a molecule in the human body called haptoglobin 2 precursor.
Type 1 diabetes and celiac disease linked via shared genetic markers
December 11, 2008 by admin · Leave a Comment
Type 1 (juvenile) diabetes and celiac disease appear to share a common genetic origin, scientists at the University of Cambridge and Barts and The London School of Medicine and Dentistry, have confirmed.
Research advances may help prevent and improve diagnosis of celiac disease
May 19, 2008 by admin · Leave a Comment
For those suffering from celiac disease, there may be good news on the horizon. New research presented today at Digestive Disease Week® 2008 (DDW®) will discuss the latest advancements in the diagnosis and prevention of celiac sprue. DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.
Scientists uncover further steps leading to celiac disease
March 2, 2008 by admin · Leave a Comment
Scientists who last year identified a new genetic risk factor for coeliac disease, have, following continued research, discovered an additional seven gene regions implicated in causing the condition. The team, lead by David van Heel, Professor of Gastrointestinal Genetics at Barts and The London School of Medicine and Dentistry, have further demonstrated that of the nine coeliac gene regions now know, four of these are also predisposing factors for type 1 diabetes. Their research sheds light not only on the nature of coeliac disease, but on the common origins of both diseases. It is published online today (2 March 2008) in Nature Genetics.
