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Promising developments in early diagnosis and treatment of mesothelioma

April 17, 2012 by admin · Leave a Comment 

New results presented at 3rd European Lung Cancer Conference in Geneva, Switzerland show important steps being made to improve the diagnosis and treatment of malignant pleural mesothelioma, an aggressive cancer of the outer lining of the lungs caused by asbestos exposure.

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Good vibrations in fight against cancer

April 16, 2012 by admin · Leave a Comment 

Medicine-toting nanochains slip into tumors and explode a chemotherapy drug into hard-to-reach cores of cancer, engineers and scientists at Case Western Reserve University report.

In tests on rats and mice, the technology took out far more cancer cells, inhibited tumor growth better and extended life longer than traditional chemotherapy delivery.

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New radiation therapy reduces treatment of gynecologic cancers from 5 weeks to 3 days

April 16, 2012 by admin · Leave a Comment 

About 71,500 women in the United States are diagnosed with a gynecologic cancer every year, according to the Centers for Disease Control. Researchers from University Hospitals Case Medical Center have developed a more effective way to treat gynecologic cancers, shortening radiation treatment time from five weeks to three days. The method will be published in the Journal of Visualized Experiments (JoVE) on April 17.

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New advances in the understanding of cancer progression

April 11, 2012 by admin · Leave a Comment 

Researchers at the Hospital de Mar Research Institute (IMIM) have discovered that the protein LOXL2 has a function within the cell nucleus thus far unknown. They have also described a new chemical reaction of this protein on histone H3 that would be involved in gene silencing, one of which would be involved in the progression of breast, larynx, lung and skin tumours.

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Breakthrough discovery unveils ‘master switches’ in colon cancer

April 11, 2012 by admin · Leave a Comment 

A team of researchers at Case Western Reserve University School of Medicine have identified a new mechanism by which colon cancer develops. By focusing on segments of DNA located between genes, or so-called “junk DNA,” the team has discovered a set of master switches, i.e., gene enhancer elements, that turn “on and off” key genes whose altered expression is defining for colon cancers. They have coined the term Variant Enhancer Loci or “VELs,” to describe these master switches.

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Study shows botanical formula fights prostate cancer

April 9, 2012 by admin · Leave a Comment 

A non-toxic, botanical formula controls aggressive human prostate tumors in mice, according to a peer-reviewed study in the The International Journal of Oncology. Researchers at Indiana University, Methodist Research Institute, showed the prostate formula significantly suppresses tumor growth in aggressive, hormone-refractory (androgen-independent) human prostate cancer cells. The study also demonstrated the formula has no toxic side effects, even at high dosages.

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Report says new evidence could tip the balance in aspirin cancer prevention care

April 8, 2012 by admin · Leave a Comment 

A new report by American Cancer Society scientists says new data showing aspirin’s potential role in reducing the risk of cancer death bring us considerably closer to the time when cancer prevention can be included in clinical guidelines for the use of aspirin in preventative care. The report, published early online in Nature Reviews Clinical Oncology, says even a 10% reduction in overall cancer incidence beginning during the first 10 years of treatment could tip the balance of benefits and risks favorably in average-risk populations.

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Novel compound demonstrates anti-leukemic effect in zebrafish, shows promise for human treatment

April 8, 2012 by admin · Leave a Comment 

A novel anti-leukemia compound with little toxicity successfully treated zebrafish with T-cell acute lymphoblastic leukemia (T-ALL), suggesting its potential to become a new highly targeted therapy for humans – even those resistant to conventional therapies – according to results from a study published online today in Blood, the Journal of the American Society of Hematology (ASH).

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Experts identify critical genes mutated in stomach cancer

April 7, 2012 by admin · Leave a Comment 

An international team of scientists, led by researchers from the Duke-NUS Graduate Medical School (Duke-NUS) in Singapore and National Cancer Centre of Singapore, has identified hundreds of novel genes that are mutated in stomach cancer, the second-most lethal cancer worldwide.

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Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC

April 3, 2012 by admin · Leave a Comment 

Long-term follow-up of a phase II clinical trial showed encouraging survival in some patients with stage 3B/4 non-small cell lung cancer treated with belagenpumatucel-L, a therapeutic vaccine. The findings were presented here at the AACR Annual Meeting 2012, held March 31 - April 4.

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