Protein found to be the link missing between HPV infection and cervical cancer development

Researchers say the discovery could offer a new screening and therapeutic strategies

Orlando, Fla. — Most women are infected with human papillomavirus (HPV), which can cause cervical cancer - yet few develop the cancer. Now researchers at Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical Center, believe they have found the missing link explaining why: activation of the beta-catenin oncogene.

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Discovery may lead to turning back the clock on ovarian cancer

Cancer researchers have discovered that a type of regulatory RNA may be effective in fighting ovarian cancer. Ovarian cancer isn’t typically discovered until it’s in the advanced stages, where it is already spreading to other organs and is very difficult to fight with chemotherapy. This new discovery may allow physicians to turn back the clock of the tumor’s life cycle to a phase where traditional chemotherapy can better do its job.

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Study suggests new treatment option to reduce metastasis in ovarian cancer

Magnetic nanoparticles

A paper published in the January issue of the journal Nanomedicine could provide the foundation for a new ovarian cancer treatment option – one that would use an outside-the-body filtration device to remove a large portion of the free-floating cancer cells that often create secondary tumors.

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Ovarian cancer advances when genes are silenced

DURHAM, N.C. – There are many mechanisms that alter the activity of genes – direct changes to the DNA code like mutations and deletions, or changes that control when genes are switched on and off, called epigenetic means. Tumor-suppressor genes are often inactivated through epigenetics, which provides an opening for the cancerous growth of cells.

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Researchers map the way to personalised treatment for ovarian cancer

Researchers have shown that point mutations – mis-spellings in a single letter of genetic code – that drive the onset and growth of cancer cells can be detected successfully in advanced ovarian cancer using a technique called OncoMap. The finding opens the way for personalised medicine in which every patient could have their tumour screened, specific mutations identified, and the appropriate drug chosen to target the mutation and halt the growth of their cancer.

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New treatment to overpower drug resistance in ovarian cancer

New research from the Centenary Institute finds a new death pathway that can break resistance

Drug resistance is a major obstacle in curing ovarian cancer but new research from the Centenary Institute has discovered a treatment that kills ovarian cancer cells in a new way that can break the resistance mechanism. Published today in Autophagy, the researchers found the drug (FTY720) had a potent effect in human ovarian cancer cells, even in those resistant to cisplatin, the most commonly used chemotherapeutic drug currently available for the treatment of ovarian cancer.

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2 studies find new genetic links to ovarian cancer risk

DURHAM, N.C. – An international consortium of scientists has discovered new genetic variants in five regions of the genome that affect the risk of ovarian cancer in the general population, according to two separate studies published today (Sunday), online in Nature Genetics.

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Researchers identify genes tied to deadliest ovarian cancers

Scientists at the Johns Hopkins Kimmel Cancer Center have identified two genes whose mutations appear to be linked to ovarian clear cell carcinoma, one of the most aggressive forms of ovarian cancer. Clear cell carcinoma is generally resistant to standard therapy.

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For some women, preventive mastectomies pay off

Study shows women with BRCA1 and BRCA2 genetic mutations significantly reduce their risk of breast and ovarian cancer with preventive surgeries

SAN ANTONIO, TX (Sept. 3) — A long-term study of women with a genetic predisposition for breast or ovarian cancer showed that those who elected major preventive surgeries had a significantly reduced risk of those cancers.

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Significant advance announced in treatment of cervical cancer

Research demonstrates that drug and radiotherapy treatment saves lives

A medical researcher at the University of Leicester has made a significant advance in the treatment of cervical cancer.

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