To predict atherosclerosis, follow the disturbed blood flow
June 22, 2010 by admin · Leave a Comment
A new animal model of atherosclerosis has allowed researchers to identify a host of genes turned on or off during the initial stages of the process, before a plaque appears in the affected blood vessel.
New atherosclerosis vaccine gives promising results
May 5, 2010 by admin · Leave a Comment
Contact: Katarina Sternudd
katarina.sternudd@ki.se
46-085-248-3895
Karolinska Institutet
A new study by researchers at the Swedish medical university Karolinska Institutet shows that the immune defence’s T cells can attack the “bad” LDL cholesterol and thereby cause an inflammation that leads to atherosclerosis. By producing a vaccine against the T cell receptors, the researchers have managed to inhibit the development of atherosclerosis in animals. The study is presented online in the distinguished periodical Journal of Experimental Medicine and is expected to be of considerable significance to the future treatment of atherosclerosis, heart attack and stroke.
Scientists discover gene module underlying atherosclerosis development
December 3, 2009 by admin · Leave a Comment
Contact: Press Officer Katarina Sternudd
katarina.sternudd@ki.se
46-852-483-895
Karolinska Institutet
By measuring the total gene activity in organs relevant for coronary artery disease (CAD), scientists at the Swedish medical university Karolinska Institutet have identified a module of genes that is important for the recruitment of white blood cells into the atherosclerotic plaque. The findings, which are to be published in the open-access journal PLoS Genetics, suggest that targeting the migration of white blood cells in the development of atherosclerosis may help to reduce the risk for adverse clinical effects such as ischemia and myocardial infarction.
New discovery may lead to immunization against cardiovascular disease
July 31, 2008 by admin · Leave a Comment
Low levels of naturally occurring antibodies may represent an increased risk of developing cardiovascular disease, particularly stroke in men. This discovery, published in the academic journal Atherosclerosis, has now led to attempts to develop an immunization against cardiovascular disease.
Genes that protect against atherosclerosis identified
March 14, 2008 by admin · Leave a Comment
One way of combating atherosclerosis is to reduce levels of “bad cholesterol” in the blood. Scientists at the Swedish medical university Karolinska Institutet have now identified the genes that bring about this beneficial effect.
