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Toronto researchers first to discover new genetic clue in the development of rheumatoid arthritis

August 13, 2011 by admin · Leave a Comment 

Findings will help lead to personalized therapies for common, complex illnesses characterized by abnormal immune responses

(August 14, 2011–Toronto, ON) Scientists at Mount Sinai Hospital, in collaboration with researchers at the University of Toronto, University Health Network and McGill University have obtained significant new insights into the causes of rheumatoid arthritis (RA) and other autoimmune disorders including type 1 diabetes, lupus and Graves disease.

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Lawson scientist presents joint pain treatment 2.0

August 8, 2011 by admin · Leave a Comment 

Dual-action Hydros-TA provides the next generation of osteoarthritis relief

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LONDON, ON – Osteoarthritis (OA) is the most common form of arthritis, affecting roughly 10% of Canadians. This degradation of the joints is painful and crippling, especially when it affects the knee. Although there are viable OA treatment options, they are short-lived and can have serious side-effects. According to Lawson Health Research Institute’s Dr. Robert Petrella, principal investigator in the COR1.0 study, the next generation of OA treatment has arrived.

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Gout prevalence swells in US over last 2 decades

July 27, 2011 by admin · Leave a Comment 

Increase in obesity and hypertension are likely contributors

A new study shows the prevalence of gout in the U.S. has risen over the last twenty years and now affects 8.3 million (4%) Americans. Prevalence of increased uric acid levels (hyperuricemia) also rose, affecting 43.3 million (21%) adults in the U.S. Greater frequency of obesity and hypertension may be associated with the jump in prevalence rates according to the findings now available in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR).

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Chloroquine finding may lead to treatments for arthritis, cancer and other diseases

July 17, 2011 by admin · Leave a Comment 

Anti-malaria drug provides key insight into potential treatments for autoimmune diseases

In a study published recently in the journal Science Signaling Van Andel Research Institute (VARI) scientists demonstrate on the molecular level how the anti-malaria drug chloroquine represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis, and certain cancers.

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Vitamin D insufficiency prevalent among psoriatic arthritis suffers

July 10, 2011 by admin · Leave a Comment 

Disease activity not affected by vitamin D levels

New research reports a high prevalence of vitamin D insufficiency and deficiency among patients with psoriatic arthritis. Seasonal variation in vitamin D levels was not observed in patients in southern or northern locations. The findings published today in Arthritis Care & Research, a journal of the American College of Rheumatology (ACR), also show no association between disease activity and vitamin D level.

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Genetic study sheds new light on auto-immune arthritis

July 9, 2011 by admin · Leave a Comment 

The team of researchers from the Universities of Bristol, Queensland (Australia), Oxford, Texas and Toronto, used a technique called genome-wide association where millions of genetic markers are measured in thousands of people that have the disease and thousands of healthy individuals.

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Progress in tissue engineering to repair joint damage in osteoarthritis

June 7, 2011 by admin · Leave a Comment 

Medical scientists now have “clear” evidence that the damaged cartilage tissue in osteoarthritis and other painful joint disorders can be encouraged to regrow and regenerate, and are developing tissue engineering technology that could help millions of patients with those disorders. That’s the conclusion of a new analysis of almost 100 scientific studies on the topic, published in ACS’s journal Molecular Pharmaceutics.

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Injectable gel could spell relief for arthritis sufferers

April 12, 2011 by admin · Leave a Comment 

Researchers at BWH create an injectable gel that could spell the future for treating arthritis

Boston, MA - Some 25 million people in the United States alone suffer from rheumatoid arthritis or its cousin osteoarthritis, diseases characterized by often debilitating pain in the joints. Now researchers at Brigham and Women’s Hospital (BWH) report an injectable gel that could spell the future for treating these diseases and others.

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Researchers explore new treatments to end OA

March 22, 2011 by admin · Leave a Comment 

Arthritis researchers from North America and Europe will convene in Chicago this week to present new osteoarthritis research that could lead to better ways to detect, treat, prevent and cure osteoarthritis (OA), which affects 27 million Americans. Hosted by the Arthritis Foundation, the Segal North American Osteoarthritis Workshop (SNOW) on March 25-27 will focus on specific forms of OA, such as those that follow joint trauma, obesity and the aging process.

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Unexpected new mechanism behind rheumatoid arthritis

February 6, 2011 by admin · Leave a Comment 

A team of researchers at the University of Gothenburg, Sweden, has identified an enzyme that protects against inflammation and joint destruction. Made when the researchers blocked production of the enzyme GGTase-I in transgenic mice, this unexpected discovery could lead to the identification of new mechanisms that control the development of inflammatory disorders, as well as new medicines.

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